randomized, control and comparative study of polyherbal formulation use for Malaria [plasmodium falciparum]

Plasmodium falciparum is the most well-known reason for extreme and life-debilitating malaria. Falciparum malaria causes more than 1 million deaths annually. Malaria remains a noteworthy reason for major morbidity and mortality in the tropics, with Plasmodium falciparum accountable for the mainstream of the disease weight and Plasmodium vivax being the geologically greatest broadly dispersed cause of malaria. The controlling of severe malaria comprises quick direction of suitable parenteral anti-malarial agents and initial acknowledgement and treatment of the complications. This clinical trial was piloted in 100 patients, in which 50 received the test drug [Malarina] and 50 received the control drug [Quinine Bisulphate]. The age range of patients was 12 years to above 50 years. The sample paired t-test was applied to evaluate the significant level. Malarina was very effective in treating malaria sign and symptoms. The new treatment Malarina was safe and well tolerated in all patients

Comparison of Anti BPH capsule [herbal] and Terazosin HCl in the treatment of benign prostate hyperplasia

Benign prostatic hyperplasia [BPH] is a disease of senile age, usually occurring> 60 years of age. BPH is a disease that involves cell proliferation of the prostate. Pathological hyperplasia affects the elements of the glandular and connective tissue of the prostate. This study is designed to scrutinize the efficacy and tolerability of herbal drug Anti BPH capsule for the management of benign prostate hyperplasia [BPH], in this study we select the 100 patients in which 50 received the Anti BPH capsule and 50 received the Terazosin HCl. We use the American Urological Association BPH Symptom Score Index Questionnaire to measure the quality of life of the patients. We compare the before treatment and after treatment results for each symptom. We record the following symptoms, incomplete emptying of bladder, Frequency, Intermittency, Urgency, Weak stream, Straining, Nocturia and weight of prostate gland by USG. We compare the both drug by using paired sample t-test. The level of significance of incomplete emptying of bladder before treatment and after treatment is 0.013 in test group and 0.032 in control group. Similarly the level of significance of Frequency before treatment and after treatment in test groups in, intermittency, Urgency, Weak stream, staining, Nocturia and mean weight of prostate gland are 0.007, 0.015, 0.044, 0.012, 0.017, 0.004 and 0.020; where as in control group afford as 0.031, 0.044, 0.044, 0.032, 0.024, 0.009 and 0.035 respectively. The herbal drug Anti BPH capsule is more effective in the treatment of BPH than Allopathic medicine Terazosin HCl

Dietary management of takayus al mebyadh [polycystic ovarian syndrome]

In Unani system of medicine the diet therapy [Ilaj bil Ghizd] is an important part for managing many diseases. Diet is one of the most important factors that keeps the Akhlat [humors] in equilibrium and ultimately maintains a balanced mizaj [temperament] on the other hand modern medicine also puts great emphasis on this aspect. PCOS [Polycystic ovarian syndrome]-insulin resistance-obesity are interconnected. The modification[s] in dietary patterns in PCOS patients improves metabolic and reproductive outcomes by reducing insulin resistance. No such article was there which accurately enlist appropriate food items for such patients. PCOS is due to Sue Mizaj-Barid Ratab [Mal temperament due to cold and moist]. Mizaj of Foods with hot and dry are the best, while cold and moist are the worst. On the other hand food with low glycemic index are best while high glycemic index should be avoided with respect to the concept of modern medicine. This review article focuses on the most healthy and unhealthy food for PCOS patients with respect to the concepts of Unani and modern medicine and enlist appropriate food items for such patients with a distinct view?

Clinical efficacy and safety of herbal medicine Dermidoc in the management of atopic dermatitis versus allopathic medicine PolymixinB-bacitrin ointment

Atopic dermatitis [AD] commonly identified as eczema. AD is an inflammatory, long-lasting, highly pruritic reverting disease of the skin. AD is classified by disease of outer skin layer barrier function. AD is progress with Immunoglobulin E facilitated sensitization to food and environmental allergens. One study stated that more than 59.6% of teen-agers with AD are at high risk of develop asthma or rhinitis. Interaction between genes and environment increase the prevalence of AD. AD have three standard stages: infantile, childhood, and adulthood. AD sign and symptoms diverge extensively. AD can be present that simply affect the hand to where a patient presents with erythroderma. AD present with erythematous papules, extremely pruritic with serous exudate. Lichenified plaques and papules are symptoms of long lasting AD. Due to outer skin layer barrier dysfunction bacterial and viral infection risk is increased in AD patients. This study was directed on 100 patients in which 50 are PolymixinB-bacitrin group and 50 are Dermidoc group. Patients were selected after seeing inclusion and exclusion criteria and taking written informed consent. Dermidoc group expressively amended skin symptoms associated with AD comparing to the PolymixinB-bacitrin group. The Dermidoc cream is effective and well tolerated. The results were analysis using paired sample t-test. The p value is <0.05. Test group [Dermidoc] were significantly more effective than PolymixinB-bacitrin group

Comparative clinical evaluation of herbal and allopathic medicine in acute tonsillitis

Tonsillitis is usually caused by a viral infection or less commonly, a bacterial infection. Symptoms may include sore throat, fever, enlargement of the tonsils, pain in swallowing, and enlarged lymph nodes around the neck. Herbal remedies are popularly used due to its potential action to relieve early tonsillitis, costeffectiveness and with fewer adverse effects. This research aimed to determine the efficacy of herbal medicine for the management of acute tonsillitis. Study was conducted at Shifa-ul-Mulk Memorial Hospital for Eastern Medicine, Madinat-ul-Hikmah, Hamdard University. Patients [n=78] were randomly assigned to receive test drug lozin [500 mg] thrice a day and control drug cephradine [250 mg] thrice a day or 500 mg twice a day for 5-12 days with a follow-up visit of 2-12 days. Both medications after a 10-day treatment period caused a significant improve-ment in all the signs and symptoms. The herbal formulation lozin demonstrated similar efficacy compared to allopathic medicine cephradine for the treatment of acute tonsillitis

Clinical evaluation of unani ear drops herbotic for earache

An ear infection [acute otitis media] is most often a bacterial or viral infection that affects the middle ear. Children as compared to adults are more are prone to infections. A study has been conducted on 200 patients with herbal medicine Herbotic and allopathic drug Ofloxacin for the treatment of otitis media. The efficacy of test and control drug was monitored before and after treatment and diagnosed on clinical history, clinical presentation and pathological investigation. This study was a case control, multicenter, prospective randomized authentic allopathic controlled, two arm parallel group clinical trial The data on clinical proforma was gathered between April 2014-March 2015 and subjected to statistical analysis. From the statistical results it was concluded that Herbotic and Ofloxacin are equally effective for the treatment of earache, effect being confirmed by physicians and patients alike

Antifungal activity of dodonaea viscosa jacq extract on pathogenic fungi isolated from super ficial skin infection

Antimicrobial activity of solvent extracts of leaves and shoot of Dodonaea viscosa Jacq have been determined against fungi, Aspergillus niger, Aspergillus flavus, Paecilomyces varioti, Microsporum gypseum, and Trichophyton rubrum causing skin diseases. All crude extracts were found to be effective against tested fungi. However chloroform has strong inhibition activity against fungi as compared to ethanol, methanol, ethylacetate and aqueous extracts. More over in present study some basic elements have been analyzed, Al, Ca, Cu, Fe, Mg, Mn, P, S and Zn from the medicinal plant Dodonaea viscosa Jacq. by using atomic absorption spectrophotometry and UV spectrophotometry. The medicinal plant Dodonaea viscosa Jacq contains considerable amount of elements which have therapeutic effects in skin diseases

Clinical evaluation of some herbal medicine for amoebiasis

Amoebiasis is a worldwide disease, particularly common in tropical countries and places where public hygiene and sanitation are poor. Amoebic infection is caused by an organism, Entamoeba histolytica [E.H.] that usually spreads through contaminated food and water. Since the causative organism of amoebiasis derives its nutrition from the normal bacterial flora of the large intestine, the latter is the chief site of infection. Aim of the study is to decrease the prevalence of Amoebic Dysentery in the community by trusted and cost-effective herbal medicinal preparation. Clinical evaluation of amoebiasis and its treatment was undertaken to evaluate the therapeutic efficacy of herbal coded medicine Amoebin Cap along with a comparative study of another Herbal Medicine Endemali, an Allopathic Medicine Entamizole DS and placebo. A randomized, clinical, comparative study has been conducted between the formulated herbal medicine Amoebin Cap, allopathic medicine Entamizole DS, herbal proprietary product Endemali and placebo to provide clinically evidence based assessments. Amoebin Cap comprises of herbs such as Phyllanthus emblica, Aegle marmelos, Holarrhena antidysenterica and Myrtus communis. The clinical evaluation involved quite a number of patients living in Karachi around 202 patients selected for the final diagnosis and treatment of amoebiasis. The clinical trial was conducted to assess the drugs and the details of which are given along with tables with its graphic representations. The number of patients assigned to test group that is Amoebin Cap were 80, while in control group 63 patients were registered to Entamizole DS and 50 patients for Endemali along with this 9 patients were kept on placebo. The data was collected in the years from 2001-2004. There were total 202 patients, the frequency of male patients were 127 [percentage of male 62.9%] while, 75 of female patients [percentage of female 37.1%] were enrolled into the study. Using a Chi-Square Test and Fisher Exact Test statistical analyses were made. All patients which were treated with Amoebin Cap showed improvement. Out of 63 patients who were treated by Entamizole DS 58 showed improvement and five did not. After applying the test of significance there was significant difference between these two drugs. Fisher Exact Test was applied and p-value was calculated as 0.015 while comparing Amoebin cap with Endemali 50 patients treated with an herbal drug Endemali. Results revealed that all patients, which were treated with Amoebin Cap, showed improvement, and out of 50 patients who were treated by Endemali 30 showed improvement and twenty did not. After applying the test of significance there was highly significant difference between these two drugs with Chi-Square Test was deduced [Yates correct] 34.81 and p-value was found to be 0.000